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GPCR

NameRelaxin receptor 2
SpeciesHomo sapiens (Human)
GeneRXFP2
SynonymRXFPR2
RXFP2
relaxin/insulin like family peptide receptor 2
relaxin receptor 2
Relaxin family peptide receptor 2
[ Show all ]
DiseaseN/A
Length754
Amino acid sequenceMIVFLVFKHLFSLRLITMFFLLHFIVLINVKDFALTQGSMITPSCQKGYFPCGNLTKCLPRAFHCDGKDDCGNGADEENCGDTSGWATIFGTVHGNANSVALTQECFLKQYPQCCDCKETELECVNGDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYAPHVRICMPLTDGISSFEDLLANNILRIFVWVIAFITCFGNLFVIGMRSFIKAENTTHAMSIKILCCADCLMGVYLFFVGIFDIKYRGQYQKYALLWMESVQCRLMGFLAMLSTEVSVLLLTYLTLEKFLVIVFPFSNIRPGKRQTSVILICIWMAGFLIAVIPFWNKDYFGNFYGKNGVCFPLYYDQTEDIGSKGYSLGIFLGVNLLAFLIIVFSYITMFCSIQKTALQTTEVRNCFGREVAVANRFFFIVFSDAICWIPVFVVKILSLFRVEIPDTMTSWIVIFFLPVNSALNPILYTLTTNFFKDKLKQLLHKHQRKSIFKIKKKSLSTSIVWIEDSSSLKLGVLNKITLGDSIMKPVS
UniProtQ8WXD0
Protein Data Bank2m96
GPCR-HGmod modelN/A
3D structure modelThis structure is from PDB ID 2m96.
BioLiPBL0278456
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL1628482
IUPHARN/A
DrugBankN/A

Ligand

NameBAS 00662566
Molecular formulaC8H12N4O3S
IUPAC namepropan-2-yl 2-[(5-oxo-3-sulfanylidene-2H-1,2,4-triazin-6-yl)amino]acetate
Molecular weight244.269
Hydrogen bond acceptor5
Hydrogen bond donor3
XlogP0.2
SynonymsAC1LE8SB
Oprea1_045329
MLS000714713
CHEMBL1349621
MolPort-000-654-261
[ Show all ]
Inchi KeyAALJFFRFEBGHPM-UHFFFAOYSA-N
Inchi IDInChI=1S/C8H12N4O3S/c1-4(2)15-5(13)3-9-6-7(14)10-8(16)12-11-6/h4H,3H2,1-2H3,(H,9,11)(H2,10,12,14,16)
PubChem CID682221
ChEMBLCHEMBL1349621
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
Potency12264.8 nMPubChem BioAssay data setChEMBL

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