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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-2 adrenergic receptor
Species	Bos taurus (Bovine)
Gene	ADRB2
Synonym	Beta-2 adrenoceptor Beta-2 adrenoreceptor
Disease	N/A for non-human GPCRs
Length	418
Amino acid sequence	MGQPGNRSVFLLAPNASHAPDQNVTLERDEAWVVGMGILMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGACHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYLAITSPFKYQCLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRASHKEAINCYAKETCCDFFTNQPYAIASSIVSFYLPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNVSQVEQDGRSGLGQRRTSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIKDNLIRKEIYILLNWLGYINSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGCSSNSNDRTDYTGEQSGYHLGEEKDSELLCEDPPGTENFVNQQGTVPSDSIDSQGRNCSTNDSLL
UniProt	Q28044
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3373
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	Procinolol
Molecular formula	C15H23NO2
IUPAC name	1-(2-cyclopropylphenoxy)-3-(propan-2-ylamino)propan-2-ol
Molecular weight	249.354
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.1
Synonyms	1-(2-cyclopropylphenoxy)-3-(propan-2-ylamino)propan-2-ol BDBM50421724 SD 2124-01 27325-36-6 AC1Q77JF Procinololum [INN-Latin] 1-(o-Cyclopropylphenoxy)-3-(isopropylamino)-2-propanol SD-2124-01 Procinolol [INN:DCF] ACM27325366 SCHEMBL1254736 27325-18-4 (mono-hydrochloride) CHEMBL1159892 AC1L2GNV Procinololum [ Show all ]
Inchi Key	RTAGQMIEWAAKMO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H23NO2/c1-11(2)16-9-13(17)10-18-15-6-4-3-5-14(15)12-7-8-12/h3-6,11-13,16-17H,7-10H2,1-2H3
PubChem CID	71707
ChEMBL	CHEMBL1159892
IUPHAR	N/A
BindingDB	50421724
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
-Log KD	9.41 -	PMID2993621	ChEMBL
Kd	0.39 nM	PMID2993621	BindingDB
Kd	0.39 nM	PMID2993621	ChEMBL

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