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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Beta-3 adrenergic receptor
Species	Rattus norvegicus (Rat)
Gene	Adrb3
Synonym	beta3-adrenoceptor beta3-adrenergic receptor Beta-3 adrenoreceptor Beta-3 adrenoceptor ADRB beta 3-AR atypical beta-adrenoceptor adrenergic receptor Adrb-3 [ Show all ]
Disease	N/A for non-human GPCRs
Length	400
Amino acid sequence	MAPWPHKNGSLAFWSDAPTLDPSAANTSGLPGVPWAAALAGALLALATVGGNLLVITAIARTPRLQTITNVFVTSLATADLVVGLLVMPPGATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGTLVTKRRARAAVVLVWIVSATVSFAPIMSQWWRVGADAEAQECHSNPRCCSFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVAKRQRRLLRRELGRFPPEESPRSPSRSPSPATVGTPTASDGVPSCGRRPARLLPLGEHRALRTLGLIMGIFSLCWLPFFLANVLRALVGPSLVPSGVFIALNWLGYANSAFNPLIYCRSPDFRDAFRRLLCSYGGRGPEEPRVVTFPASPVASRQNSPLNRFDGYEGERPFPT
UniProt	P26255
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4031
IUPHAR	30
DrugBank	N/A

Ligand

Name	Prenalterol
Molecular formula	C12H19NO3
IUPAC name	4-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenol
Molecular weight	225.288
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	1.4
Synonyms	CHEMBL1160714 Hyprenan Prenalterol [INN:BAN] 4-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenol A-Ba-C-50,005 BDBM50421716 FT-0630699 LS-104700 S-Varbian (S)-1-(4-hydroxyphenoxy)-3-(1-methylethyl)amino-2-propanol ADUKCCWBEDSMEB-NSHDSACASA-N C07533 H-133-22 Phenol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, (S)- ZINC897007 (S)-Prenalterol 58165-86-9 API0006933 CHEBI:8391 D0JK0I KB-211509 Prenalterolum 4-[(2S)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]phenol AC1L27QA BRN 5740338 GTPL537 M4G34404CX SCHEMBL249753 (S)-4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)phenol AJ-24264 CC-33915 H-80-62 4-[(2S)-2-hydroxy-3-(isopropylamino)propoxy]phenol 61260-05-7 (hydrochloride) AX8149043 EINECS 260-791-5 KWD-2033 Prenalterolum [INN-Latin] (-)-Prenalterol 4-{[(2s)-2-hydroxy-3-(isopropylamino)propyl]oxy}phenol AC1Q579K C-12776 H 133/22 PHENOL METABOLITE UNII-M4G34404CX (S)-4-(2-Hydroxy-3-(isopropylamino)propoxy)phenol 57526-81-5 AKOS016014110 CGP 7760B [ Show all ]
Inchi Key	ADUKCCWBEDSMEB-NSHDSACASA-N
Inchi ID	InChI=1S/C12H19NO3/c1-9(2)13-7-11(15)8-16-12-5-3-10(14)4-6-12/h3-6,9,11,13-15H,7-8H2,1-2H3/t11-/m0/s1
PubChem CID	42396
ChEMBL	CHEMBL1160714
IUPHAR	537
BindingDB	50421716
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
ED50	0.27 mg.kg-1	PMID1350309	ChEMBL

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