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GPCR

NameNeuropeptides B/W receptor type 1
SpeciesHomo sapiens (Human)
GeneNPBWR1
SynonymG protein-coupled receptor 7
G-protein coupled receptor 7
GPR7
neuropeptides B/W receptor type 1
NPBW1 receptor
DiseaseN/A
Length328
Amino acid sequenceMDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
UniProtP48145
Protein Data BankN/A
GPCR-HGmod modelP48145
3D structure modelThis predicted structure model is from GPCR-EXP P48145.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL1293293
IUPHARN/A
DrugBankN/A

Ligand

NameCHEMBL1965555
Molecular formulaC19H15ClN2O5
IUPAC name2-[[4-chloro-5-(4-methoxyphenoxy)-6-oxopyridazin-1-yl]methyl]benzoic acid
Molecular weight386.788
Hydrogen bond acceptor6
Hydrogen bond donor1
XlogP3.0
SynonymsSR-02000001362
SR-02000001362-1
Inchi KeyBTTUMLDCCQYDFM-UHFFFAOYSA-N
Inchi IDInChI=1S/C19H15ClN2O5/c1-26-13-6-8-14(9-7-13)27-17-16(20)10-21-22(18(17)23)11-12-4-2-3-5-15(12)19(24)25/h2-10H,11H2,1H3,(H,24,25)
PubChem CID53356633
ChEMBLCHEMBL1965555
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
IC50<20000.0 nMPubChem BioAssay data setChEMBL

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