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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Mu-type opioid receptor
Species	Bos taurus (Bovine)
Gene	OPRM1
Synonym	M-OR-1 MOR-1
Disease	N/A for non-human GPCRs
Length	401
Amino acid sequence	MDSGAVPTNASNCTDPFTHPSSCSPAPSPSSWVNFSHLEGNLSDPCGPNRTELGGSDRLCPSAGSPSMITAIIIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDLRTPRNAKIINICNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPILIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETTPLP
UniProt	P79350
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3041
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL409026
Molecular formula	C15H21NO2
IUPAC name	10-amino-9-(hydroxymethyl)-1-methyltricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol
Molecular weight	247.338
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	2.2
Synonyms	BDBM50050484 10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.02,7]trideca-2,4,6-trien-4-ol
Inchi Key	TYULFMDMDFGHME-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H21NO2/c1-14-5-4-13(16)15(8-14,9-17)7-10-2-3-11(18)6-12(10)14/h2-3,6,13,17-18H,4-5,7-9,16H2,1H3
PubChem CID	44301664
ChEMBL	CHEMBL409026
IUPHAR	N/A
BindingDB	50050484
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	40.6 nM	PMID8642554	BindingDB,ChEMBL
Ki	41.0 nM	PMID8642554	BindingDB
Ki	41.2 nM	PMID8642554	ChEMBL

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