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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A1
Species	Bos taurus (Bovine)
Gene	ADORA1
Synonym	N/A
Disease	N/A for non-human GPCRs
Length	326
Amino acid sequence	MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
UniProt	P28190
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4975
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	7-Methyl-[1,8]naphthyridin-4-ylamine
Molecular formula	C9H9N3
IUPAC name	7-methyl-1,8-naphthyridin-4-amine
Molecular weight	159.192
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	1.2
Synonyms	AKOS006323720 SCHEMBL6392289 BDBM50147860 1568-91-8 CHEMBL102126 ZINC13579580 BURICQOPQKPYBQ-UHFFFAOYSA-N 4-amino-7-methyl-[1,8]-naphthyridine FT-0706199 [ Show all ]
Inchi Key	BURICQOPQKPYBQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C9H9N3/c1-6-2-3-7-8(10)4-5-11-9(7)12-6/h2-5H,1H3,(H2,10,11,12)
PubChem CID	12455201
ChEMBL	CHEMBL102126
IUPHAR	N/A
BindingDB	50147860
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<10000.0 nM	PMID15163184	BindingDB,ChEMBL

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