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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Gastrin-releasing peptide receptor
Species	Rattus norvegicus (Rat)
Gene	Grpr
Synonym	BB2 BB2 receptor gastrin-releasing peptide receptor GRP-preferring bombesin receptor GRP-R
Disease	N/A for non-human GPCRs
Length	384
Amino acid sequence	MDPNNCSHLNLEVDPFLSCNNTFNQTLNPPKMDNWFHPGIIYVIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFSDLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPSLLNRSHSTGRSTTCMTSFKSTNPSATFSLINGNICHEGYV
UniProt	P52500
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4280
IUPHAR	39
DrugBank	N/A

Ligand

Name	CHEMBL385761
Molecular formula	C52H70N14O9
IUPAC name	(2S)-N-[2-[[(2S)-1-[[(2S)-1-acetamido-4-methylpentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-acetamido-3-phenylpropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanamide
Molecular weight	1035.22
Hydrogen bond acceptor	11
Hydrogen bond donor	12
XlogP	2.2
Synonyms	N/A
Inchi Key	UEWFJIVZXYBRKX-PIVAMLDBSA-N
Inchi ID	InChI=1S/C52H70N14O9/c1-29(2)17-38(25-55-32(6)67)62-49(72)43(20-36-23-53-27-58-36)63-45(69)26-57-52(75)46(30(3)4)66-47(70)31(5)60-48(71)42(19-35-22-56-40-16-12-11-15-39(35)40)64-51(74)44(21-37-24-54-28-59-37)65-50(73)41(61-33(7)68)18-34-13-9-8-10-14-34/h8-16,22-24,27-31,38,41-44,46,56H,17-21,25-26H2,1-7H3,(H,53,58)(H,54,59)(H,55,67)(H,57,75)(H,60,71)(H,61,68)(H,62,72)(H,63,69)(H,64,74)(H,65,73)(H,66,70)/t31-,38-,41+,42-,43-,44-,46-/m0/s1
PubChem CID	44361852
ChEMBL	CHEMBL385761
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Release	2.9 %	PMID1469698	ChEMBL
Release	3.6 %	PMID1469698	ChEMBL
Release	3.7 %	PMID1469698	ChEMBL
Release	16.7 %	PMID1469698	ChEMBL
Release	20.2 %	PMID1469698	ChEMBL

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