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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cysteinyl leukotriene receptor 1
Species	Cavia porcellus (Guinea pig)
Gene	CYSLTR1
Synonym	CysLTR1 Cysteinyl leukotriene D4 receptor LTD4 receptor
Disease	N/A for non-human GPCRs
Length	340
Amino acid sequence	MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
UniProt	Q2NNR5
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5645
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL287559
Molecular formula	C24H14BrNO5S
IUPAC name	2-[3-(1,3-benzothiazol-2-ylmethoxy)phenyl]-6-bromo-4-oxochromene-8-carboxylic acid
Molecular weight	508.342
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.4
Synonyms	2-[3-[(2-Benzothiazolyl)methoxy]phenyl]-4-oxo-6-bromo-4H-1-benzopyran-8-carboxylic acid 2-[3-(Benzothiazol-2-ylmethoxy)-phenyl]-6-bromo-4-oxo-4H-chromene-8-carboxylic acid BDBM50064066 SCHEMBL6175301
Inchi Key	BZNPRZMJMTTYCW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H14BrNO5S/c25-14-9-16-19(27)11-20(31-23(16)17(10-14)24(28)29)13-4-3-5-15(8-13)30-12-22-26-18-6-1-2-7-21(18)32-22/h1-11H,12H2,(H,28,29)
PubChem CID	10553667
ChEMBL	CHEMBL287559
IUPHAR	N/A
BindingDB	50064066
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Kd	79.0 nM	PMID9554876	BindingDB,ChEMBL

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