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Name | Mu-type opioid receptor |
---|---|
Species | Cavia porcellus (Guinea pig) |
Gene | OPRM1 |
Synonym | M-OR-1 MOR-1 |
Disease | N/A for non-human GPCRs |
Length | 98 |
Amino acid sequence | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI |
UniProt | P97266 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4354 |
IUPHAR | N/A |
DrugBank | N/A |
Name | Etorphine |
---|---|
Molecular formula | C25H33NO4 |
IUPAC name | 19-(2-hydroxypentan-2-yl)-15-methoxy-5-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11,16-tetraen-11-ol |
Molecular weight | 411.542 |
Hydrogen bond acceptor | 5 |
Hydrogen bond donor | 2 |
XlogP | 3.1 |
Synonyms | 19-Propylorvinol FT-0668440 Tetrahydro-7-.alpha.-(2-hydroxy-2-pentyl)-6,14-endo-ethenooripavine 6,14-Ethenomorphinan-7-methanol, 4,5-epoxy-3-hydroxy-6-methoxy-.alpha.,17-dimethyl-.alpha.-propyl-, [5.alpha.,7.alpha.(R)]- CAHCBJPUTCKATP-UHFFFAOYSA-N [ Show all ] |
Inchi Key | CAHCBJPUTCKATP-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C25H33NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,9-10,17-18,21,27-28H,5,8,11-14H2,1-4H3 |
PubChem CID | 518962 |
ChEMBL | N/A |
IUPHAR | 1625 |
BindingDB | 82425 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Ki | 1.5 nM | PMID9686407 | BindingDB |
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