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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	B2 bradykinin receptor
Species	Cavia porcellus (Guinea pig)
Gene	BDKRB2
Synonym	B2R BK-2 receptor
Disease	N/A for non-human GPCRs
Length	372
Amino acid sequence	MFNITSQVSALNATLAQGNSCLDAEWWSWLNTIQAPFLWVLFVLAVLENIFVLSVFFLHKSSCTVAEIYLGNLAVADLILAFGLPFWAITIANNFDWLFGEVLCRMVNTMIQMNMYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCALLLSSPMLVFRTMKDYRDEGHNVTACLIIYPSLTWQVFTNVLLNLVGFLLPLSIITFCTVQIMQVLRNNEMQKFKEIQTERRATVLVLAVLLLFVVCWLPFQIGTFLDTLRLLGFLPGCWEHVIDLITQISSYLAYSNSCLNPLVYVIVGKRFRKKSREVYHGLCRSGGCVSEPAQSENSMGTLRTSISVDRQIHKLQDWARSSSEGTPPGLL
UniProt	O70526
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4111
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL556176
Molecular formula	C20H20BrCl2N5O3
IUPAC name	N-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichlorophenyl]-N-methyl-2-(methylcarbamoylamino)acetamide
Molecular weight	529.216
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.4
Synonyms	SCHEMBL8564948 BDBM50062899 N-Methyl-N-[2,4-dichloro-3-[(2-methyl-3-bromoimidazo[1,2-a]pyridin-8-yl)oxymethyl]phenyl]-2-(3-methylureido)acetamide CHEMBL1196218 N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-2-(3-methyl-ureido)-acetamide; hydrochloride
Inchi Key	CBBTUOINAJEZOJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H20BrCl2N5O3/c1-11-18(21)28-8-4-5-15(19(28)26-11)31-10-12-13(22)6-7-14(17(12)23)27(3)16(29)9-25-20(30)24-2/h4-8H,9-10H2,1-3H3,(H2,24,25,30)
PubChem CID	10792291
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50062899
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	46.0 nM	PMID9484506	BindingDB

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