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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Cannabinoid receptor 2
Species	Mus musculus (Mouse)
Gene	Cnr2
Synonym	Peripheral cannabinoid receptor mCB2 CB2-R CB2 receptor CB2 CB-2 cannabinoid receptor 2 (spleen) cannabinoid receptor 2 (macrophage) rCB2 [ Show all ]
Disease	N/A for non-human GPCRs
Length	347
Amino acid sequence	MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
UniProt	P47936
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5373
IUPHAR	57
DrugBank	N/A

Ligand

Name	CHEMBL149691
Molecular formula	C24H43NO2
IUPAC name	(5Z,8Z,11Z,14Z)-1-[(1-hydroxy-2-methylpropan-2-yl)amino]icosa-5,8,11,14-tetraen-1-ol
Molecular weight	377.613
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	6.1
Synonyms	(5Z,8Z,11Z,14Z)-1-(2-Hydroxy-1,1-dimethyl-ethylamino)-icosa-5,8,11,14-tetraen-1-ol BDBM50072773
Inchi Key	AFDIXUDCQBFWPO-GKFVBPDJSA-N
Inchi ID	InChI=1S/C24H43NO2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23(27)25-24(2,3)22-26/h8-9,11-12,14-15,17-18,23,25-27H,4-7,10,13,16,19-22H2,1-3H3/b9-8-,12-11-,15-14-,18-17-
PubChem CID	44366841
ChEMBL	CHEMBL149691
IUPHAR	N/A
BindingDB	50072773
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	3690.0 nM	PMID9876105	BindingDB,ChEMBL

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