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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Trace amine-associated receptor 1
Species	Homo sapiens (Human)
Gene	TAAR1
Synonym	trace amine receptor 1 TAR1 TaR-1 TA1 receptor TRAR1
Disease	N/A
Length	339
Amino acid sequence	MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
UniProt	Q96RJ0
Protein Data Bank	N/A
GPCR-HGmod model	Q96RJ0
3D structure model	This predicted structure model is from GPCR-EXP Q96RJ0.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5857
IUPHAR	364
DrugBank	BE0001044

Ligand

Name	SMR000011654
Molecular formula	C17H20ClNOS
IUPAC name	3-(3-phenylpyrrolidin-1-yl)-1-thiophen-2-ylpropan-1-one;hydrochloride
Molecular weight	321.863
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	None
Synonyms	SR-01000472329-1 MLS000035953 AC1MFEMN SR-01000472329-3 CHEMBL1411785 3-(3-phenylpyrrolidin-1-yl)-1-thiophen-2-ylpropan-1-one hydrochloride MolPort-002-119-108 SR-01000472329 AKOS030513485 MCULE-1471816326 425655-22-7 REGID_for_CID_2893244 [ Show all ]
Inchi Key	CHLNWFGCKBBGIO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H19NOS.ClH/c19-16(17-7-4-12-20-17)9-11-18-10-8-15(13-18)14-5-2-1-3-6-14;/h1-7,12,15H,8-11,13H2;1H
PubChem CID	2893244
ChEMBL	CHEMBL1411785
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
EC50	156.78 nM	PubChem BioAssay data set	ChEMBL
IC50	1494.0 nM	PubChem BioAssay data set	ChEMBL

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