You can:
Name | G-protein coupled receptor 55 |
---|---|
Species | Homo sapiens (Human) |
Gene | GPR55 |
Synonym | GPR55 |
Disease | N/A |
Length | 319 |
Amino acid sequence | MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG |
UniProt | Q9Y2T6 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9Y2T6 |
3D structure model | This predicted structure model is from GPCR-EXP Q9Y2T6. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1075322 |
IUPHAR | 109 |
DrugBank | BE0005802 |
Name | NSC610996 |
---|---|
Molecular formula | C18H16N2OS |
IUPAC name | 3,3-diphenyl-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-2-one |
Molecular weight | 308.399 |
Hydrogen bond acceptor | 2 |
Hydrogen bond donor | 0 |
XlogP | 3.6 |
Synonyms | AC1L77LF CHEMBL3220949 3,3-Diphenyl-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-2(3H)-one ZINC1611635 AC1Q6ION [ Show all ] |
Inchi Key | ZFEOUZINYPNLSJ-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C18H16N2OS/c21-16-18(14-8-3-1-4-9-14,15-10-5-2-6-11-15)20-12-7-13-22-17(20)19-16/h1-6,8-11H,7,12-13H2 |
PubChem CID | 356017 |
ChEMBL | CHEMBL3220949 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Activity | 53.0 % | MedChemComm, (2014) 5:5:632 | ChEMBL |
IC50 | <10000.0 nM | MedChemComm, (2014) 5:5:632 | ChEMBL |
Inhibition | 2.0 % | MedChemComm, (2014) 5:5:632 | ChEMBL |
zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218