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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Free fatty acid receptor 4
Species	Homo sapiens (Human)
Gene	FFAR4
Synonym	PGR4 Omega-3 fatty acid receptor 1 O3FAR1 GT01 GPR129 GPR120 G-protein-coupled receptor GT01 G-protein coupled receptor PGR4 FFA4 receptor G-protein coupled receptor 129 G-protein coupled receptor 120 G protein-coupled receptor 129 G protein-coupled receptor 120 G-protein coupled receptor GT01 [ Show all ]
Disease	N/A
Length	377
Amino acid sequence	MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
UniProt	Q5NUL3
Protein Data Bank	N/A
GPCR-HGmod model	Q5NUL3
3D structure model	This predicted structure model is from GPCR-EXP Q5NUL3.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5339
IUPHAR	127
DrugBank	BE0003399

Ligand

Name	CHEMBL3311314
Molecular formula	C16H19NO2S
IUPAC name	4-methyl-N-(2,4,6-trimethylphenyl)benzenesulfonamide
Molecular weight	289.393
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.9
Synonyms	ST45184523 AC1LI7NH MolPort-000-563-578 [(4-methylphenyl)sulfonyl](2,4,6-trimethylphenyl)amine ANVUKJDKJYJFNE-UHFFFAOYSA-N N-Mesityl-p-toluenesulfonamide 4-methyl-N-(2,4,6-trimethylphenyl)benzenesulfonamide STL257144 AH-357/04334005 N-(p-toluenesulfonyl)-2,4,6-trimethylaniline BDBM50044857 SCHEMBL5848352 MCULE-7091054407 ZINC514226 AKOS002346282 N-mesityl-4-methylbenzenesulfonamide [ Show all ]
Inchi Key	ANVUKJDKJYJFNE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H19NO2S/c1-11-5-7-15(8-6-11)20(18,19)17-16-13(3)9-12(2)10-14(16)4/h5-10,17H,1-4H3
PubChem CID	925016
ChEMBL	CHEMBL3311314
IUPHAR	N/A
BindingDB	50044857
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	1000.0 nM	PMID24881566	BindingDB,ChEMBL
Rmax	83.0 %	PMID24881566	ChEMBL

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