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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Sus scrofa (Pig)
Gene	DRD1
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	P50130
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5067
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3318840
Molecular formula	C58H72Cl2F2N2O6
IUPAC name	bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] hexadecanedioate
Molecular weight	1002.12
Hydrogen bond acceptor	10
Hydrogen bond donor	0
XlogP	14.6
Synonyms	BDBM50053385
Inchi Key	APANCCIVVADHPY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C58H72Cl2F2N2O6/c59-49-27-23-47(24-28-49)57(35-41-63(42-36-57)39-13-15-53(65)45-19-31-51(61)32-20-45)69-55(67)17-11-9-7-5-3-1-2-4-6-8-10-12-18-56(68)70-58(48-25-29-50(60)30-26-48)37-43-64(44-38-58)40-14-16-54(66)46-21-33-52(62)34-22-46/h19-34H,1-18,35-44H2
PubChem CID	118709168
ChEMBL	CHEMBL3318840
IUPHAR	N/A
BindingDB	50053385
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	6800.0 nM	PMID25047579	BindingDB,ChEMBL

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