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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Muscarinic acetylcholine receptor M2
Species	Sus scrofa (Pig)
Gene	CHRM2
Synonym	N/A
Disease	N/A for non-human GPCRs
Length	466
Amino acid sequence	MNNSTNSSNSGLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQEPVSPSLVQGRIVKPNNNNMPGSDEALEHNKIQNGKAPRDAVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIKIVTKTQKSDSCTPANTTVELVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
UniProt	P06199
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4781
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3337867
Molecular formula	C44H54Br2N4
IUPAC name	(1S,9Z,11S,13S,17S,25Z,27S,28S,33S,35S,36S,38S)-28,38-diethyl-14,30-bis(prop-2-enyl)-8,24-diaza-14,30-diazoniaundecacyclo[25.5.2.211,14.11,26.110,17.02,7.013,17.018,23.030,33.08,35.024,36]octatriaconta-2,4,6,9,18,20,22,25-octaene;dibromide
Molecular weight	798.752
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	None
Synonyms	BDBM50025027
Inchi Key	CHMFXMOIXRFSOW-SKYHGZCBSA-L
Inchi ID	InChI=1S/C44H54N4.2BrH/c1-5-19-47-21-17-43-35-13-9-11-15-37(35)45-26-34-32-24-40-44(18-22-48(40,20-6-2)28-30(32)8-4)36-14-10-12-16-38(36)46(42(34)44)25-33(41(43)45)31(23-39(43)47)29(7-3)27-47;;/h5-6,9-16,25-26,29-32,39-42H,1-2,7-8,17-24,27-28H2,3-4H3;2*1H/q+2;;/p-2/b33-25-,34-26-;;/t29-,30-,31+,32+,39+,40+,41+,42+,43-,44-,47?,48?;;/m1../s1
PubChem CID	118714980
ChEMBL	CHEMBL3337867
IUPHAR	N/A
BindingDB	50025027
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
EC50	36.0 nM	PMID25192059	BindingDB,ChEMBL
EC50	36.31 nM	PMID25192059	ChEMBL

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