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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Bos taurus (Bovine)
Gene	DRD1
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	Q95136
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2967
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL325818
Molecular formula	C24H25BrN2O2
IUPAC name	N-[[(3S)-1-benzylpyrrolidin-3-yl]methyl]-4-bromo-1-methoxynaphthalene-2-carboxamide
Molecular weight	453.38
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.0
Synonyms	BDBM50132698 N-[[(3S)-1-Benzyl-3alpha-pyrrolidinyl]methyl]-1-methoxy-4-bromonaphthalene-2-carboxamide 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((S)-1-benzyl-pyrrolidin-3-ylmethyl)-amide
Inchi Key	CNAWUGXPLJMOSN-SFHVURJKSA-N
Inchi ID	InChI=1S/C24H25BrN2O2/c1-29-23-20-10-6-5-9-19(20)22(25)13-21(23)24(28)26-14-18-11-12-27(16-18)15-17-7-3-2-4-8-17/h2-10,13,18H,11-12,14-16H2,1H3,(H,26,28)/t18-/m0/s1
PubChem CID	44340376
ChEMBL	CHEMBL325818
IUPHAR	N/A
BindingDB	50132698
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	2100.0 nM	PMID12951112	BindingDB,ChEMBL
Ki	2900.0 nM	PMID12951112	BindingDB,ChEMBL

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