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GPCR

NameDelta-type opioid receptor
SpeciesSus scrofa (Pig)
GeneOPRD1
SynonymDOR-1
D-OR-1
DiseaseN/A for non-human GPCRs
Length228
Amino acid sequenceGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILVITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
UniProtP79291
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL4103
IUPHARN/A
DrugBankN/A

Ligand

NameHomocysteine thiolactone
Molecular formulaC4H7NOS
IUPAC name(3S)-3-aminothiolan-2-one
Molecular weight117.166
Hydrogen bond acceptor3
Hydrogen bond donor1
XlogP-0.1
Synonyms(3S)-3-aminodihydrothiophen-2(3H)-one
(3S)-3-aminothiolan-2-one
(S)-3-aminodihydro-2(3H)-thiophenone
(S)-3-Aminodihydrothiophen-2(3H)-one
06DCC220-D06A-4793-8958-6383A1C2218C
[ Show all ]
Inchi KeyKIWQWJKWBHZMDT-VKHMYHEASA-N
Inchi IDInChI=1S/C4H7NOS/c5-3-1-2-7-4(3)6/h3H,1-2,5H2/t3-/m0/s1
PubChem CID134505
ChEMBLN/A
IUPHARN/A
BindingDB86198
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
Ki<10000.0 nMPMID12649361BindingDB

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