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Name | Delta-type opioid receptor |
---|---|
Species | Sus scrofa (Pig) |
Gene | OPRD1 |
Synonym | D-OR-1 DOR-1 |
Disease | N/A for non-human GPCRs |
Length | 228 |
Amino acid sequence | GIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILVITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL |
UniProt | P79291 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4103 |
IUPHAR | N/A |
DrugBank | N/A |
Name | DPDPE |
---|---|
Molecular formula | C30H39N5O7S2 |
IUPAC name | (4S,7S,13S)-13-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid |
Molecular weight | 645.79 |
Hydrogen bond acceptor | 10 |
Hydrogen bond donor | 7 |
XlogP | -0.6 |
Synonyms | H-Tyr-c(D-Pen-Gly-Phe-D-Pen)-OH Tyr-D-Pen-Gly-Phe-D-Pen [Disulfide Bridge: 2-5] [D-Pen2,5]Enkephalin 1,2-Dithia-5,8,11-triazacyclotetradecane, cyclic peptide deriv. AC1L2XHZ [ Show all ] |
Inchi Key | MCMMCRYPQBNCPH-WMIMKTLMSA-N |
Inchi ID | InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1 |
PubChem CID | 104787 |
ChEMBL | CHEMBL31421 |
IUPHAR | 1608 |
BindingDB | 21008 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has more than 5 hydrogen bond donor. This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Ki | 0.3 nM | PMID9686407 | BindingDB |
Ki | 2.8 nM | PMID9686407 | BindingDB |
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