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GPCR

NameDelta-type opioid receptor
SpeciesSus scrofa (Pig)
GeneOPRD1
SynonymD-OR-1
DOR-1
DiseaseN/A for non-human GPCRs
Length228
Amino acid sequenceGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILVITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
UniProtP79291
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL4103
IUPHARN/A
DrugBankN/A

Ligand

Name(-)-Normorphine
Molecular formulaC16H17NO3
IUPAC name1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
Molecular weight271.316
Hydrogen bond acceptor4
Hydrogen bond donor3
XlogP0.3
SynonymsBDBM85329
Morphinan-3,6.alpha.-diol, 7,8-didehydro-4,5.alpha.-epoxy-
4,6-dihydroxymorphin-7-ene
FT-0673117
NSC270042
[ Show all ]
Inchi KeyONBWJWYUHXVEJS-UHFFFAOYSA-N
Inchi IDInChI=1S/C16H17NO3/c18-11-3-1-8-7-10-9-2-4-12(19)15-16(9,5-6-17-10)13(8)14(11)20-15/h1-4,9-10,12,15,17-19H,5-7H2
PubChem CID430245
ChEMBLN/A
IUPHARN/A
BindingDB85329
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
Ki60.5 nMPMID9686407BindingDB

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