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GPCR

NameDelta-type opioid receptor
SpeciesSus scrofa (Pig)
GeneOPRD1
SynonymDOR-1
D-OR-1
DiseaseN/A for non-human GPCRs
Length228
Amino acid sequenceGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILVITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
UniProtP79291
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL4103
IUPHARN/A
DrugBankN/A

Ligand

Namequercetin
Molecular formulaC15H10O7
IUPAC name2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one
Molecular weight302.238
Hydrogen bond acceptor7
Hydrogen bond donor5
XlogP1.5
Synonyms117-39-5
Meletin
Sophoretin
Quercetine
Xanthaurine
[ Show all ]
Inchi KeyREFJWTPEDVJJIY-UHFFFAOYSA-N
Inchi IDInChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
PubChem CID5280343
ChEMBLCHEMBL50
IUPHARN/A
BindingDB7460
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
Ki<10000.0 nMPMID12110997BindingDB

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