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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C-C chemokine receptor-like 2
Species	Homo sapiens (Human)
Gene	CCRL2
Synonym	ACR5 CRAM-B CRAM-A CKRX Chemokine receptor X Chemokine receptor CCR11 CCRL2 CCR6 CCR11 Putative MCP-1 chemokine receptor [ Show all ]
Disease	N/A
Length	344
Amino acid sequence	MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV
UniProt	O00421
Protein Data Bank	N/A
GPCR-HGmod model	O00421
3D structure model	This predicted structure model is from GPCR-EXP O00421.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2321627
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL9999174
Molecular formula	C26H30F3N7O
IUPAC name	N-[1-[4-[3-(methylamino)pyridin-4-yl]cyclohexyl]azetidin-3-yl]-2-[[6-(trifluoromethyl)quinazolin-4-yl]amino]acetamide
Molecular weight	513.569
Hydrogen bond acceptor	10
Hydrogen bond donor	3
XlogP	3.9
Synonyms	BDBM163447 N-(1-(4-(3-(methylamino)pyridin-4-yl)cyclohexyl)azetidin-3-yl)-2-((6-(trifluoromethyl)quinazolin-4-yl)amino)acetamide US9062048, 74 CHEMBL3704091 SIMPHXXRRUXIKA-UHFFFAOYSA-N
Inchi Key	SIMPHXXRRUXIKA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H30F3N7O/c1-30-23-11-31-9-8-20(23)16-2-5-19(6-3-16)36-13-18(14-36)35-24(37)12-32-25-21-10-17(26(27,28)29)4-7-22(21)33-15-34-25/h4,7-11,15-16,18-19,30H,2-3,5-6,12-14H2,1H3,(H,35,37)(H,32,33,34)
PubChem CID	68004048
ChEMBL	CHEMBL3704091
IUPHAR	N/A
BindingDB	163447
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	130.0 nM	, None	BindingDB,ChEMBL

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