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GPCR

NameDelta-type opioid receptor
SpeciesSus scrofa (Pig)
GeneOPRD1
SynonymDOR-1
D-OR-1
DiseaseN/A for non-human GPCRs
Length228
Amino acid sequenceGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILVITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
UniProtP79291
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL4103
IUPHARN/A
DrugBankN/A

Ligand

Namepentazocine
Molecular formulaC19H27NO
IUPAC name(1R,9R,13R)-1,13-dimethyl-10-(3-methylbut-2-enyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol
Molecular weight285.431
Hydrogen bond acceptor2
Hydrogen bond donor1
XlogP3.3
SynonymsL-pentazocine
Pentazocinum
Pentazocaine
Pentazocina
Liticon
[ Show all ]
Inchi KeyVOKSWYLNZZRQPF-GDIGMMSISA-N
Inchi IDInChI=1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m0/s1
PubChem CID441278
ChEMBLCHEMBL560
IUPHAR1606
BindingDB50001028
DrugBankDB00652

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
Ki32.7 nMPMID9686407BindingDB

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