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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A1
Species	Cavia porcellus (Guinea pig)
Gene	ADORA1
Synonym	N/A
Disease	N/A for non-human GPCRs
Length	326
Amino acid sequence	MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD
UniProt	P47745
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2304404
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL609233
Molecular formula	C19H25N7O3S
IUPAC name	(3R,4S,5S)-2-[6-(cyclopentylamino)purin-9-yl]-5-[(1-methylimidazol-2-yl)sulfanylmethyl]oxolane-3,4-diol
Molecular weight	431.515
Hydrogen bond acceptor	9
Hydrogen bond donor	3
XlogP	1.6
Synonyms	BDBM50452004
Inchi Key	CSGICLCLXOKRJK-PZGKNFOESA-N
Inchi ID	InChI=1S/C19H25N7O3S/c1-25-7-6-20-19(25)30-8-12-14(27)15(28)18(29-12)26-10-23-13-16(21-9-22-17(13)26)24-11-4-2-3-5-11/h6-7,9-12,14-15,18,27-28H,2-5,8H2,1H3,(H,21,22,24)/t12-,14-,15-,18?/m1/s1
PubChem CID	46876090
ChEMBL	CHEMBL609233
IUPHAR	N/A
BindingDB	50452004
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
CPA	112.0 %	PMID15203164	ChEMBL
Ki	1338.0 nM	PMID15203164	BindingDB
Ki low	1338.0 nM	PMID15203164	ChEMBL

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