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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Probable G-protein coupled receptor 174
Species	Homo sapiens (Human)
Gene	GPR174
Synonym	FKSG79 GPR174
Disease	N/A
Length	333
Amino acid sequence	MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSGNRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMAQDLGEKQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC
UniProt	Q9BXC1
Protein Data Bank	N/A
GPCR-HGmod model	Q9BXC1
3D structure model	This predicted structure model is from GPCR-EXP Q9BXC1.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3562167
IUPHAR	145
DrugBank	N/A

Ligand

Name	CHEMBL3577162
Molecular formula	C25H48NO9P
IUPAC name	(2S,3S)-2-amino-3-[hydroxy-[(2R)-2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropoxy]phosphoryl]oxybutanoic acid
Molecular weight	537.631
Hydrogen bond acceptor	10
Hydrogen bond donor	4
XlogP	2.6
Synonyms	BDBM50096584 (2S,3S)-2-Amino-3-[[1-O-[(9Z)-9-octadecenoyl]-L-glycero-3-phospho]oxy]butanoic acid
Inchi Key	TUOGAVKNETYDTH-IKZNXBAASA-N
Inchi ID	InChI=1S/C25H48NO9P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(28)33-19-22(27)20-34-36(31,32)35-21(2)24(26)25(29)30/h10-11,21-22,24,27H,3-9,12-20,26H2,1-2H3,(H,29,30)(H,31,32)/b11-10-/t21-,22+,24-/m0/s1
PubChem CID	101780960
ChEMBL	CHEMBL3577162
IUPHAR	N/A
BindingDB	50096584
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	830.0 nM	PMID25970039	BindingDB,ChEMBL
EC50	831.76 nM	PMID25970039	ChEMBL
EC50	832.0 nM	PMID25970039	BindingDB

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