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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Taste receptor type 2 member 14
Species	Homo sapiens (Human)
Gene	TAS2R14
Synonym	T2R14 TAS2R14 Taste receptor family B member 1 taste receptor, type 2, member 14 TRB1
Disease	N/A
Length	317
Amino acid sequence	MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS
UniProt	Q9NYV8
Protein Data Bank	N/A
GPCR-HGmod model	Q9NYV8
3D structure model	This predicted structure model is from GPCR-EXP Q9NYV8.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3309105
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	4-(dibenzylsulfamoyl)benzoic Acid
Molecular formula	C21H19NO4S
IUPAC name	4-(dibenzylsulfamoyl)benzoic acid
Molecular weight	381.446
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.6
Synonyms	BDBM211106 SMR000543366 HMS2871D21 ZINC5533661 AKOS003605819 MolPort-002-632-840 102479-27-6 STL053368 4-(N,N-dibenzylsulfamoyl)benzoic acid MCULE-4133597102 AYAKDXHPTOEADO-UHFFFAOYSA-N SCHEMBL1278616 CHEMBL1523162 US9247759, 5-28 AC1NC2X3 MLS001214900 [ Show all ]
Inchi Key	AYAKDXHPTOEADO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H19NO4S/c23-21(24)19-11-13-20(14-12-19)27(25,26)22(15-17-7-3-1-4-8-17)16-18-9-5-2-6-10-18/h1-14H,15-16H2,(H,23,24)
PubChem CID	4552362
ChEMBL	CHEMBL1523162
IUPHAR	N/A
BindingDB	211106
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	7740.0 nM	None	ChEMBL
IC50	7740.0 nM	N/A	BindingDB

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