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GPCR

NameProbable G-protein coupled receptor 34
SpeciesHomo sapiens (Human)
GeneGPR34
SynonymGPR34
DiseaseN/A
Length381
Amino acid sequenceMRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSEFKPGYSLHDTSVAVKIQSSSKST
UniProtQ9UPC5
Protein Data BankN/A
GPCR-HGmod modelQ9UPC5
3D structure modelThis predicted structure model is from GPCR-EXP Q9UPC5.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3562165
IUPHAR101
DrugBankN/A

Ligand

NameSCHEMBL3499675
Molecular formulaC30H23ClFN3O4
IUPAC name2-[[7-(4-chlorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]amino]-3-[4-[(3-fluorophenyl)methoxy]phenyl]propanoic acid
Molecular weight543.979
Hydrogen bond acceptor6
Hydrogen bond donor2
XlogP6.8
SynonymsCHEMBL3718204
Inchi KeyCVAIBYVVROUPSO-UHFFFAOYSA-N
Inchi IDInChI=1S/C30H23ClFN3O4/c31-23-8-6-21(7-9-23)22-12-13-35-17-27(33-28(35)16-22)29(36)34-26(30(37)38)15-19-4-10-25(11-5-19)39-18-20-2-1-3-24(32)14-20/h1-14,16-17,26H,15,18H2,(H,34,36)(H,37,38)
PubChem CID59335682
ChEMBLCHEMBL3718204
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Experimental Data

ParameterValueReferenceDatabase source
IC501000.0 nMNoneChEMBL

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