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GPCR

Name	Olfactory receptor 5K1
Species	Homo sapiens (Human)
Gene	OR5K1
Synonym	HTPCRX10 Olfactory receptor OR3-8
Disease	N/A
Length	308
Amino acid sequence	MAEENHTMKNEFILTGFTDHPELKTLLFVVFFAIYLITVVGNISLVALIFTHRRLHTPMYIFLGNLALVDSCCACAITPKMLENFFSENKRISLYECAVQFYFLCTVETADCFLLAAMAYDRYVAICNPLQYHIMMSKKLCIQMTTGAFIAGNLHSMIHVGLVFRLVFCGSNHINHFYCDILPLYRLSCVDPYINELVLFIFSGSVQVFTIGSVLISYLYILLTIFKMKSKEGRAKAFSTCASHFLSVSLFYGSLFFMYVRPNLLEEGDKDIPAAILFTIVVPLLNPFIYSLRNREVISVLRKILMKK
UniProt	Q8NHB7
Protein Data Bank	N/A
GPCR-HGmod model	Q8NHB7
3D structure model	This predicted structure model is from GPCR-EXP Q8NHB7.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3721312
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	54464-57-2
Molecular formula	C16H26O
IUPAC name	1-(2,3,8,8-tetramethyl-1,3,4,5,6,7-hexahydronaphthalen-2-yl)ethanone
Molecular weight	234.383
Hydrogen bond acceptor	1
Hydrogen bond donor	0
XlogP	3.6
Synonyms	SCHEMBL111407 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-tetramethyl-2-naphthyl)ethan-1-one 2-Acetonaphthone-1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl AM806777 CTK5A1137 Ethanone,1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)- LS-185877 NCGC00090712-01 Tox21_303483 1-(2,3,8,8-tetramethyl-1,3,4,5,6,7-hexahydronaphthalen-2-yl)ethanone BBL028399 DSSTox_GSID_31290 i-e-super NCGC00258907-01 W-111089 1',2',3',4',5',6',7',8'-Octahydro-2',3',8',8'-tetramethyl-2'-acetonaphthone 1GD7ODM28Y AC1Q5CUV EINECS 259-174-3 Isocyclemone E STL352821 1-(2,3,8,8-tetramethyl-1,2,3,4,5,6,7,8-octahydro-naphthalen-2-yl)-ethanone 239809-44-0 Amberix Super (Iso E Super) Derambrene FT-0670449 MCULE-2137893098 NCGC00090712-02 UNII-1GD7ODM28Y 1616297-46-1 7-acetyl-1,2,3,4,5,6,7,8-octahydro-1,1,6,7-tetramethyl-naphthalene Boisvelone DSSTox_RID_78869 Iso E Super OTNE 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)ethanone 2-Acetonaphthone, 1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl- AKOS015955684 CHEMBL1423553 Ethanone, 1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)- KB-146310 MolPort-002-506-991 Tox21_201355 1-(2,3,8,8-tetramethyl-1,2,3,4,5,6,7,8-octahydronaphthalen-2-yl)ethanone 464T572 AN-40510 DSSTox_CID_11290 FVUGZKDGWGKCFE-UHFFFAOYSA-N NCGC00257507-01 UNII-2JU6ZH6GRE component FVUGZKDGWGKCFE-UHFFFAOYSA-N 166090-45-5 AC1L33LQ CAS-54464-57-2 DTXSID7031290 Iso-E super [ Show all ]
Inchi Key	FVUGZKDGWGKCFE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H26O/c1-11-9-13-7-6-8-15(3,4)14(13)10-16(11,5)12(2)17/h11H,6-10H2,1-5H3
PubChem CID	108242
ChEMBL	CHEMBL1423553
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	75.0 %	None	ChEMBL

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