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GPCR

NameProbable G-protein coupled receptor 34
SpeciesHomo sapiens (Human)
GeneGPR34
SynonymGPR34
DiseaseN/A
Length381
Amino acid sequenceMRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSEFKPGYSLHDTSVAVKIQSSSKST
UniProtQ9UPC5
Protein Data BankN/A
GPCR-HGmod modelQ9UPC5
3D structure modelThis predicted structure model is from GPCR-EXP Q9UPC5.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3562165
IUPHAR101
DrugBankN/A

Ligand

NameCHEMBL3717036
Molecular formulaC30H25ClFN3O4
IUPAC name2-[[7-(4-chlorophenyl)-3,8a-dihydroimidazo[1,2-a]pyridine-2-carbonyl]amino]-3-[4-[(2-fluorophenyl)methoxy]phenyl]propanoic acid
Molecular weight545.995
Hydrogen bond acceptor7
Hydrogen bond donor2
XlogP5.4
SynonymsN/A
Inchi KeyLNFRLPIVEQEBCG-UHFFFAOYSA-N
Inchi IDInChI=1S/C30H25ClFN3O4/c31-23-9-7-20(8-10-23)21-13-14-35-17-27(33-28(35)16-21)29(36)34-26(30(37)38)15-19-5-11-24(12-6-19)39-18-22-3-1-2-4-25(22)32/h1-14,16,26,28H,15,17-18H2,(H,34,36)(H,37,38)
PubChem CID127024309
ChEMBLCHEMBL3717036
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Experimental Data

ParameterValueReferenceDatabase source
IC501000.0 nMNoneChEMBL

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