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GPCR

NameProbable G-protein coupled receptor 34
SpeciesHomo sapiens (Human)
GeneGPR34
SynonymGPR34
DiseaseN/A
Length381
Amino acid sequenceMRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSEFKPGYSLHDTSVAVKIQSSSKST
UniProtQ9UPC5
Protein Data BankN/A
GPCR-HGmod modelQ9UPC5
3D structure modelThis predicted structure model is from GPCR-EXP Q9UPC5.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3562165
IUPHAR101
DrugBankN/A

Ligand

NameSCHEMBL5273551
Molecular formulaC30H23ClFN3O4
IUPAC name2-[[6-(4-chlorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]amino]-3-[4-[(4-fluorophenyl)methoxy]phenyl]propanoic acid
Molecular weight543.979
Hydrogen bond acceptor6
Hydrogen bond donor2
XlogP6.8
SynonymsCHEMBL3718021
Inchi KeyQJINHOLALXGEQU-UHFFFAOYSA-N
Inchi IDInChI=1S/C30H23ClFN3O4/c31-23-8-5-21(6-9-23)22-7-14-28-33-27(17-35(28)16-22)29(36)34-26(30(37)38)15-19-3-12-25(13-4-19)39-18-20-1-10-24(32)11-2-20/h1-14,16-17,26H,15,18H2,(H,34,36)(H,37,38)
PubChem CID59335909
ChEMBLCHEMBL3718021
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Experimental Data

ParameterValueReferenceDatabase source
IC501000.0 nMNoneChEMBL

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