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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Putative P2Y purinoceptor 10
Species	Mus musculus (Mouse)
Gene	P2ry10
Synonym	P2RY10 P2Y10 purinergic receptor P2Y purinergic receptor P2Y, G-protein coupled 10 purinergic receptor P2Y10
Disease	N/A for non-human GPCRs
Length	328
Amino acid sequence	MGSNSTSSAESNCNATYLPFQYSLYATTYIFIFIPGLLANSAALWVLCRFISKKNKAIIFMINLSVADLAHILSLPLRIYYYINRHWPFQRALCLLCFYLKYLNMYASIFFLTCISLQRCLFLLKPFRARNWKRRYDVGISAVIWIVVGTACLPFPILRNAGLANSTDSCFADLGYKQMDAVVLVTMVVIAELAGFVIPVITIACCTWKTTVSLKHPPIAFQGISERKKALRMVFMCAAVFVICFTPYHINFIFYTMVKESIITSCPTVKSTLYFHPFSLCLASLCCLLDPILYYFMASEFRDQLSRHGSSVTRSRLMSRESGSSMVN
UniProt	Q8BFU7
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3562168
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3814362
Molecular formula	C27H50NO9P
IUPAC name	(2S)-2-amino-3-[hydroxy-[(2R,3S)-2-[[(Z)-octadec-9-enoyl]oxymethyl]oxan-3-yl]oxyphosphoryl]oxypropanoic acid
Molecular weight	563.669
Hydrogen bond acceptor	10
Hydrogen bond donor	3
XlogP	3.2
Synonyms	BDBM50177122 SCHEMBL15928002
Inchi Key	VWKCFDZBVNFTLU-AUMIFUJISA-N
Inchi ID	InChI=1S/C27H50NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-26(29)35-22-25-24(18-17-20-34-25)37-38(32,33)36-21-23(28)27(30)31/h9-10,23-25H,2-8,11-22,28H2,1H3,(H,30,31)(H,32,33)/b10-9-/t23-,24-,25+/m0/s1
PubChem CID	78319777
ChEMBL	CHEMBL3814362
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	450.0 nM	PMID27077565	ChEMBL
EC50	457.09 nM	PMID27077565	ChEMBL
Emax	3.9 %	PMID27077565	ChEMBL
Intrinsic activity	0.0014 -	PMID27077565	ChEMBL

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