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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 4
Species	Rattus norvegicus (Rat)
Gene	Htr4
Synonym	5-HT-4 5-HT4 5-HT4 receptor 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled serotonin receptor 4
Disease	N/A for non-human GPCRs
Length	406
Amino acid sequence	MDRLDANVSSNEGFGSVEKVVLLTFFAMVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVNAFGAIELVQDIWFYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDVIEKRKFNHNSNSTFCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQTADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEKVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPVIRRPQDNDLEDSCSLKRSQS
UniProt	Q62758
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4317
IUPHAR	9
DrugBank	N/A

Ligand

Name	CHEMBL314299
Molecular formula	C25H31ClN4O
IUPAC name	1-benzyl-6-chloro-N-[[1-(2-methylpropyl)piperidin-4-yl]methyl]benzimidazole-4-carboxamide
Molecular weight	439.0
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.1
Synonyms	1-Benzyl-6-chloro-1H-benzoimidazole-4-carboxylic acid (1-isobutyl-piperidin-4-ylmethyl)-amide BDBM50105631 N-(1-Isobutylpiperidine-4-ylmethyl)-1-benzyl-6-chloro-1H-benzimidazole-4-carboxamide
Inchi Key	CXYKHLAUAZCSIS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H31ClN4O/c1-18(2)15-29-10-8-19(9-11-29)14-27-25(31)22-12-21(26)13-23-24(22)28-17-30(23)16-20-6-4-3-5-7-20/h3-7,12-13,17-19H,8-11,14-16H2,1-2H3,(H,27,31)
PubChem CID	21588627
ChEMBL	CHEMBL314299
IUPHAR	N/A
BindingDB	50105631
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	69.18 nM	PMID11597405	ChEMBL
Ki	69.2 nM	PMID11597405, PMID12383006	BindingDB,ChEMBL

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