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GPCR

NameFree fatty acid receptor 4
SpeciesHomo sapiens (Human)
GeneFFAR4
SynonymO3FAR1
G-protein coupled receptor 120
GPR120
G-protein-coupled receptor GT01
G-protein coupled receptor PGR4
[ Show all ]
DiseaseN/A
Length377
Amino acid sequenceMSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
UniProtQ5NUL3
Protein Data BankN/A
GPCR-HGmod modelQ5NUL3
3D structure modelThis predicted structure model is from GPCR-EXP Q5NUL3.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5339
IUPHAR127
DrugBankBE0003399

Ligand

NameDC260126
Molecular formulaC16H18FNO2S
IUPAC nameN-(4-butylphenyl)-4-fluorobenzenesulfonamide
Molecular weight307.383
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP4.4
Synonyms346692-04-4
N-(4-butylphenyl)-4-fluorobenzenesulfonamide
CHEMBL3931570
AC1MDUI6
Oprea1_825888
[ Show all ]
Inchi KeyCNGHPXKWPGIDSK-UHFFFAOYSA-N
Inchi IDInChI=1S/C16H18FNO2S/c1-2-3-4-13-5-9-15(10-6-13)18-21(19,20)16-11-7-14(17)8-12-16/h5-12,18H,2-4H2,1H3
PubChem CID2843133
ChEMBLCHEMBL3931570
IUPHARN/A
BindingDB50196405
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
EC505370.0 nMPMID27570890BindingDB
EC505370.32 nMPMID27570890ChEMBL
Emax76.0 %PMID27570890ChEMBL

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