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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	SCHEMBL1990370
Molecular formula	C19H19N5O
IUPAC name	6-pyrazol-1-yl-N-(4-pyrrolidin-3-ylphenyl)pyridine-3-carboxamide
Molecular weight	333.395
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	1.7
Synonyms	US9452980, 73 3-Pyridinecarboxamide, 6-(1H-pyrazol-1-yl)-N-[4-(3-pyrrolidinyl)phenyl]- CHEMBL3900637 1312567-10-4 BDBM250163
Inchi Key	CTMWZMVXWWFSTF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H19N5O/c25-19(16-4-7-18(21-13-16)24-11-1-9-22-24)23-17-5-2-14(3-6-17)15-8-10-20-12-15/h1-7,9,11,13,15,20H,8,10,12H2,(H,23,25)
PubChem CID	53250929
ChEMBL	CHEMBL3900637
IUPHAR	N/A
BindingDB	250163
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	5.6 nM	, None	BindingDB,ChEMBL

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