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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Uracil nucleotide/cysteinyl leukotriene receptor
Species	Homo sapiens (Human)
Gene	GPR17
Synonym	GPR17 P2Y-like receptor G-protein coupled receptor 17 R12 UDP/CysLT receptor uracil nucleotide/cysteinyl leukotriene receptor [ Show all ]
Disease	N/A
Length	367
Amino acid sequence	MSKRSWWAGSRKPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSFEGKTNESSLSAKSEL
UniProt	Q13304
Protein Data Bank	N/A
GPCR-HGmod model	Q13304
3D structure model	This predicted structure model is from GPCR-EXP Q13304.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075162
IUPHAR	88
DrugBank	N/A

Ligand

Name	CHEMBL3968577
Molecular formula	C18H15NO4
IUPAC name	3-(2-carboxyethyl)-6-phenyl-1H-indole-2-carboxylic acid
Molecular weight	309.321
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	3.3
Synonyms	3-(2-carboxyethyl)-6-phenyl-1H-indole-2-carboxylic acid GDRVFNVJBQRHAM-UHFFFAOYSA-N SCHEMBL14739168
Inchi Key	GDRVFNVJBQRHAM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H15NO4/c20-16(21)9-8-14-13-7-6-12(11-4-2-1-3-5-11)10-15(13)19-17(14)18(22)23/h1-7,10,19H,8-9H2,(H,20,21)(H,22,23)
PubChem CID	71280862
ChEMBL	CHEMBL3968577
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	724.44 nM	None	ChEMBL

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