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GPCR

NameOxoeicosanoid receptor 1
SpeciesHomo sapiens (Human)
GeneOXER1
SynonymOXE receptor
5-oxo-ETE receptor
5-oxo-ETE G-protein coupled receptor
TG1019
oxoeicosanoid (OXE) receptor 1
[ Show all ]
DiseaseN/A
Length423
Amino acid sequenceMLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPSFSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGSSQG
UniProtQ8TDS5
Protein Data BankN/A
GPCR-HGmod modelQ8TDS5
3D structure modelThis predicted structure model is from GPCR-EXP Q8TDS5.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL1628461
IUPHAR271
DrugBankN/A

Ligand

NameEicosatrienoic acid
Molecular formulaC20H34O2
IUPAC name(11Z,14Z,17Z)-icosa-11,14,17-trienoic acid
Molecular weight306.49
Hydrogen bond acceptor2
Hydrogen bond donor1
XlogP6.9
Synonyms(Z,Z,Z)-11,14,17-Eicosatrienoic acid
11,14,17-Icosatrienoic acid
17046-59-2
Icosatrienoic acid
11,14,17-Eicosatrienoic acid
[ Show all ]
Inchi KeyAHANXAKGNAKFSK-PDBXOOCHSA-N
Inchi IDInChI=1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10H,2,5,8,11-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-
PubChem CID5312529
ChEMBLCHEMBL453991
IUPHARN/A
BindingDB50269535
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Experimental Data

ParameterValueReferenceDatabase source
IC502000.0 nMPMID24351031BindingDB,ChEMBL

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