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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Free fatty acid receptor 4
Species	Mus musculus (Mouse)
Gene	Ffar4
Synonym	Omega-3 fatty acid receptor 1 O3FAR1 GT01 GPR129 GPR120 G-protein-coupled receptor GT01 G-protein coupled receptor GT01 G-protein coupled receptor 120 G protein-coupled receptor 129 G protein-coupled receptor 120 FFA4 receptor PGR4 [ Show all ]
Disease	N/A for non-human GPCRs
Length	361
Amino acid sequence	MSPECAQTTGPGPSHTLDQVNRTHFPFFSDVKGDHRLVLSVVETTVLGLIFVVSLLGNVCALVLVARRRRRGATASLVLNLFCADLLFTSAIPLVLVVRWTEAWLLGPVVCHLLFYVMTMSGSVTILTLAAVSLERMVCIVRLRRGLSGPGRRTQAALLAFIWGYSALAALPLCILFRVVPQRLPGGDQEIPICTLDWPNRIGEISWDVFFVTLNFLVPGLVIVISYSKILQITKASRKRLTLSLAYSESHQIRVSQQDYRLFRTLFLLMVSFFIMWSPIIITILLILIQNFRQDLVIWPSLFFWVVAFTFANSALNPILYNMSLFRNEWRKIFCCFFFPEKGAIFTDTSVRRNDLSVISS
UniProt	Q7TMA4
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2052036
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3941880
Molecular formula	C18H13FN2O3S
IUPAC name	2-(3-fluoro-5-pyridin-2-yloxyphenyl)-3H-1,2-benzothiazole 1,1-dioxide
Molecular weight	356.371
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.1
Synonyms	BDBM50196394 J3.563.114C 2-[3-Fluoro-5-(2-pyridinyloxy)phenyl]-2,3-dihydro-1,2-benzoisothiazole 1,1-dioxide
Inchi Key	LDMHZAQFLWCKDT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H13FN2O3S/c19-14-9-15(11-16(10-14)24-18-7-3-4-8-20-18)21-12-13-5-1-2-6-17(13)25(21,22)23/h1-11H,12H2
PubChem CID	86280676
ChEMBL	CHEMBL3941880
IUPHAR	N/A
BindingDB	50196394
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	147.91 nM	PMID27570890	ChEMBL
EC50	148.0 nM	PMID27570890	BindingDB
EC50	478.63 nM	PMID27570890	ChEMBL
EC50	479.0 nM	PMID27570890	BindingDB

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