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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Lysophosphatidic acid receptor 5
Species	Homo sapiens (Human)
Gene	LPAR5
Synonym	G-protein coupled receptor 92 LPAR5 LPA5 receptor LPA-5 LPA receptor 5 G protein-coupled receptor 92 GPR92 G-protein coupled receptor 93 GPR93 [ Show all ]
Disease	N/A
Length	372
Amino acid sequence	MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSLSSFTQCPQDSAL
UniProt	Q9H1C0
Protein Data Bank	N/A
GPCR-HGmod model	Q9H1C0
3D structure model	This predicted structure model is from GPCR-EXP Q9H1C0.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5700
IUPHAR	124
DrugBank	N/A

Ligand

Name	CHEMBL3945517
Molecular formula	C26H25NO5
IUPAC name	4-[[cyclopropylmethyl-[4-(2-methoxyphenoxy)benzoyl]amino]methyl]benzoic acid
Molecular weight	431.488
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.6
Synonyms	ZINC584598397 BDBM251695 SCHEMBL16506976 US9464060, 31
Inchi Key	UCZBTVNWIVAWQV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H25NO5/c1-31-23-4-2-3-5-24(23)32-22-14-12-20(13-15-22)25(28)27(16-18-6-7-18)17-19-8-10-21(11-9-19)26(29)30/h2-5,8-15,18H,6-7,16-17H2,1H3,(H,29,30)
PubChem CID	117903311
ChEMBL	CHEMBL3945517
IUPHAR	N/A
BindingDB	251695
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	5.0 nM	, None	BindingDB,ChEMBL

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