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GPCR

NameNeuropeptides B/W receptor type 1
SpeciesHomo sapiens (Human)
GeneNPBWR1
SynonymG protein-coupled receptor 7
G-protein coupled receptor 7
GPR7
neuropeptides B/W receptor type 1
NPBW1 receptor
DiseaseN/A
Length328
Amino acid sequenceMDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
UniProtP48145
Protein Data BankN/A
GPCR-HGmod modelP48145
3D structure modelThis predicted structure model is from GPCR-EXP P48145.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL1293293
IUPHARN/A
DrugBankN/A

Ligand

NameCHEMBL1992695
Molecular formulaC19H13Cl3N2O4
IUPAC name5-chloro-2-[2-(2,4-dichlorophenyl)-2-oxoethyl]-4-(4-methoxyphenoxy)pyridazin-3-one
Molecular weight439.673
Hydrogen bond acceptor5
Hydrogen bond donor0
XlogP4.7
SynonymsSR-02000001264
SR-02000001264-1
Inchi KeyDAIZAQYOXCJXEB-UHFFFAOYSA-N
Inchi IDInChI=1S/C19H13Cl3N2O4/c1-27-12-3-5-13(6-4-12)28-18-16(22)9-23-24(19(18)26)10-17(25)14-7-2-11(20)8-15(14)21/h2-9H,10H2,1H3
PubChem CID53234168
ChEMBLCHEMBL1992695
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
IC501850.0 nMPubChem BioAssay data setChEMBL

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