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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Free fatty acid receptor 4
Species	Mus musculus (Mouse)
Gene	Ffar4
Synonym	Omega-3 fatty acid receptor 1 O3FAR1 GT01 GPR129 GPR120 G-protein-coupled receptor GT01 G-protein coupled receptor GT01 G-protein coupled receptor 120 G protein-coupled receptor 129 G protein-coupled receptor 120 FFA4 receptor PGR4 [ Show all ]
Disease	N/A for non-human GPCRs
Length	361
Amino acid sequence	MSPECAQTTGPGPSHTLDQVNRTHFPFFSDVKGDHRLVLSVVETTVLGLIFVVSLLGNVCALVLVARRRRRGATASLVLNLFCADLLFTSAIPLVLVVRWTEAWLLGPVVCHLLFYVMTMSGSVTILTLAAVSLERMVCIVRLRRGLSGPGRRTQAALLAFIWGYSALAALPLCILFRVVPQRLPGGDQEIPICTLDWPNRIGEISWDVFFVTLNFLVPGLVIVISYSKILQITKASRKRLTLSLAYSESHQIRVSQQDYRLFRTLFLLMVSFFIMWSPIIITILLILIQNFRQDLVIWPSLFFWVVAFTFANSALNPILYNMSLFRNEWRKIFCCFFFPEKGAIFTDTSVRRNDLSVISS
UniProt	Q7TMA4
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2052036
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3985509
Molecular formula	C22H19FO4
IUPAC name	4-[4-(2-fluoro-5-phenoxyphenyl)phenoxy]butanoic acid
Molecular weight	366.388
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.0
Synonyms	BDBM50203670
Inchi Key	ZSQHPVMBVGKLJL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H19FO4/c23-21-13-12-19(27-18-5-2-1-3-6-18)15-20(21)16-8-10-17(11-9-16)26-14-4-7-22(24)25/h1-3,5-6,8-13,15H,4,7,14H2,(H,24,25)
PubChem CID	134157586
ChEMBL	CHEMBL3985509
IUPHAR	N/A
BindingDB	50203670
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Activity	80.0 %	PMID27815121	ChEMBL
EC50	29.0 nM	PMID27815121	BindingDB,ChEMBL

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