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GPCR

NameFree fatty acid receptor 3
SpeciesHomo sapiens (Human)
GeneFFAR3
SynonymFFA3R
FFA3 receptor
G-protein coupled receptor 41
GPCR41
GPR41
[ Show all ]
DiseaseN/A
Length346
Amino acid sequenceMDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES
UniProtO14843
Protein Data BankN/A
GPCR-HGmod modelO14843
3D structure modelThis predicted structure model is from GPCR-EXP O14843.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5201
IUPHAR227
DrugBankN/A

Ligand

Namebutyric acid
Molecular formulaC4H8O2
IUPAC namebutanoic acid
Molecular weight88.106
Hydrogen bond acceptor2
Hydrogen bond donor1
XlogP0.8
Synonymsbutanoic acid
n-Butyric acid
107-92-6
n-Butanoic acid
propylformic acid
[ Show all ]
Inchi KeyFERIUCNNQQJTOY-UHFFFAOYSA-N
Inchi IDInChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)
PubChem CID264
ChEMBLN/A
IUPHAR1059
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
EC5012589.3 - 158489.0 nMPMID12496283, PMID12711604, PMID14722361, PMID21220428IUPHAR

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