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GPCR

NameP2Y purinoceptor 13
SpeciesHomo sapiens (Human)
GeneP2RY13
SynonymP2Y13
G-protein coupled receptor 86
purinergic receptor P2Y, G-protein coupled 13
G-protein coupled receptor 94
GPR94
[ Show all ]
DiseaseN/A
Length354
Amino acid sequenceMTAAIRRQRELSILPKVTLEAMNTTVMQGFNRSERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLPCMQGRKTTASSQENHSSQTDNITLG
UniProtQ9BPV8
Protein Data BankN/A
GPCR-HGmod modelQ9BPV8
3D structure modelThis predicted structure model is from GPCR-EXP Q9BPV8.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLN/A
IUPHAR329
DrugBankN/A

Ligand

NameAdpbetas
Molecular formulaC10H15N5O9P2S
IUPAC name[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydroxyphosphinothioyl hydrogen phosphate
Molecular weight443.264
Hydrogen bond acceptor14
Hydrogen bond donor6
XlogP-2.9
Synonymsadenosine 5'-O-(2-thiodiphosphate)
beta-Thio-ADP
Adenosine-5'-O-(2-thiodiphosphate)
CHEMBL335206
35094-45-2
[ Show all ]
Inchi KeyHCIKUKNAJRJFOW-KQYNXXCUSA-N
Inchi IDInChI=1S/C10H15N5O9P2S/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(23-10)1-22-25(18,19)24-26(20,21)27/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H2,11,12,13)(H2,20,21,27)/t4-,6-,7-,10-/m1/s1
PubChem CID5310996
ChEMBLCHEMBL335206
IUPHAR1755
BindingDB50118230
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has more than 5 hydrogen bond donor.
This ligand has more than 10 hydrogen bond acceptor.

Experimental Data

ParameterValueReferenceDatabase source
IC501995.26 nMPMID12815166IUPHAR

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