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GPCR

NameP2Y purinoceptor 4
SpeciesRattus norvegicus (Rat)
GeneP2ry4
SynonymP2Y4
pyrimidinergic receptor P2Y
pyrimidinoceptor
UNR
P2Y4 receptor
[ Show all ]
DiseaseN/A for non-human GPCRs
Length361
Amino acid sequenceMTSAESLLFTSLGPSPSSGDGDCRFNEEFKFILLPMSYAVVFVLGLALNAPTLWLFLFRLRPWDATATYMFHLALSDTLYVLSLPTLVYYYAARNHWPFGTGLCKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRAIRWGRPRFASLLCLGVWLVVAGCLVPNLFFVTTNANGTTILCHDTTLPEEFDHYVYFSSAVMVLLFGLPFLITLVCYGLMARRLYRPLPGAGQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYQARLLQADCHVLNIVNVVYKVTRPLASANSCLDPVLYLFTGDKYRNQLQQLCRGSKPKPRTAASSLALVTLHEESISRWADTHQDSTFSAYEGDRL
UniProtO35811
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2124
IUPHAR325
DrugBankN/A

Ligand

NameAffi gel blue
Molecular formulaC29H20ClN7O11S3
IUPAC name1-amino-4-[4-[[4-chloro-6-(3-sulfoanilino)-1,3,5-triazin-2-yl]amino]-3-sulfoanilino]-9,10-dioxoanthracene-2-sulfonic acid
Molecular weight774.147
Hydrogen bond acceptor18
Hydrogen bond donor7
XlogP4.4
SynonymsCibacron Blue F 3GA
Cibacron Blue 3G
Cibacronblau F3G-A
Procion Blue H-B
C.I. Reactive Blue 2
[ Show all ]
Inchi KeyJQYMGXZJTCOARG-UHFFFAOYSA-N
Inchi IDInChI=1S/C29H20ClN7O11S3/c30-27-35-28(33-13-4-3-5-15(10-13)49(40,41)42)37-29(36-27)34-18-9-8-14(11-20(18)50(43,44)45)32-19-12-21(51(46,47)48)24(31)23-22(19)25(38)16-6-1-2-7-17(16)26(23)39/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37)
PubChem CID656725
ChEMBLN/A
IUPHAR1739
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has more than 5 hydrogen bond donor.
This ligand has more than 10 hydrogen bond acceptor.
This ligand is heavier than 500 daltons.

Experimental Data

ParameterValueReferenceDatabase source
IC5019952.6 nMPMID9647463IUPHAR

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