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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 6
Species	Rattus norvegicus (Rat)
Gene	P2ry6
Synonym	P2Y ATP receptor 6 P2Y purinoceptor 6 P2Y6 P2Y6 receptor pyrimidinergic receptor P2Y uridine nucleotide receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	328
Amino acid sequence	MERDNGTIQAPGLPPTTCVYREDFKRLLLPPVYSVVLVVGLPLNVCVIAQICASRRTLTRSAVYTLNLALADLLYACSLPLLIYNYARGDHWPFGDLACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWVVCGVVWLVVTAQCLPTAVFAATGIQRNRTVCYDLSPPILSTRYLPYGMALTVIGFLLPFTALLACYCRMARRLCRQDGPAGPVAQERRSKAARMAVVVAAVFVISFLPFHITKTAYLAVRSTPGVSCPVLETFAAAYKGTRPFASANSVLDPILFYFTQQKFRRQPHDLLQKLTAKWQRQRV
UniProt	Q63371
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3543
IUPHAR	326
DrugBank	N/A

Ligand

Name	MRS2567
Molecular formula	C16H12N2S2
IUPAC name	1-isothiocyanato-4-[2-(4-isothiocyanatophenyl)ethyl]benzene
Molecular weight	296.406
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	6.1
Synonyms	1-isothiocyanato-4-[2-(4-isothiocyanatophenyl)ethyl]benzene D0V4FT SCHEMBL1853024 GTPL1752 1,2-di-(4-isothiocyanatophenyl)ethane 4,4'-Diisothiocyanatobibenzyl [ Show all ]
Inchi Key	KGPFLJVFCCOOEO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H12N2S2/c19-11-17-15-7-3-13(4-8-15)1-2-14-5-9-16(10-6-14)18-12-20/h3-10H,1-2H2
PubChem CID	11266452
ChEMBL	N/A
IUPHAR	1752
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	100.0 nM	PMID15081875	IUPHAR

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