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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Ovarian cancer G-protein coupled receptor 1
Species	Homo sapiens (Human)
Gene	GPR68
Synonym	Ovarian cancer G-protein coupled receptor 1 OGR1 OGR-1 GPR68 GPR12A G-protein coupled receptor 68 sphingosylphosphorylcholine receptor [ Show all ]
Disease	N/A
Length	365
Amino acid sequence	MGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQIKARNELGVYLCNLTVADLFYICSLPFWLQYVLQHDNWSHGDLSCQVCGILLYENIYISVGFLCCISVDRYLAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHEEVIEDENQHRVCFEHYPIQAWQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLACFLPYHVLLLVRSVWEASCDFAKGVFNAYHFSLLLTSFNCVADPVLYCFVSETTHRDLARLRGACLAFLTCSRTGRAREAYPLGAPEASGKSGAQGEEPELLTKLHPAFQTPNSPGSGGFPTGRLA
UniProt	Q15743
Protein Data Bank	N/A
GPCR-HGmod model	Q15743
3D structure model	This predicted structure model is from GPCR-EXP Q15743.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3713916
IUPHAR	114
DrugBank	N/A

Ligand

Name	Ogerin
Molecular formula	C17H17N5O
IUPAC name	[2-[4-amino-6-(benzylamino)-1,3,5-triazin-2-yl]phenyl]methanol
Molecular weight	307.357
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	2.2
Synonyms	GTPL9155 [2-[4-amino-6-(benzylamino)-1,3,5-triazin-2-yl]phenyl]methanol MolPort-019-806-689 Z2289799517 J3.499.357B {2-[4-amino-6-(benzylamino)-1,3,5-triazin-2-yl]phenyl}methanol 1309198-71-7 AKOS027322977 ZINC67740571 MCULE-9613033770 2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol Ogerin, >=98% (HPLC) [ Show all ]
Inchi Key	MDGIEDNDSFMSLP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H17N5O/c18-16-20-15(14-9-5-4-8-13(14)11-23)21-17(22-16)19-10-12-6-2-1-3-7-12/h1-9,23H,10-11H2,(H3,18,19,20,21,22)
PubChem CID	56707820
ChEMBL	N/A
IUPHAR	9155
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
KB	10715.0 nM	PMID26550826	IUPHAR

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