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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 1F
Species	Mus musculus (Mouse)
Gene	Htr1f
Synonym	HTR1EL 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 5-HT6 5-HT1F receptor 5-HT1F 5-HT1Ebeta 5-HT-1F 5-HT-1E-beta serotonin receptor 1F [ Show all ]
Disease	N/A for non-human GPCRs
Length	366
Amino acid sequence	MDFLNASDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVLCDIWLSVDIICCTCSILHLSAIALDRYRAITDAVEYARKRTPRHAGIMITIVWVISVFISMPPLFWRHQGTSRDDECVIKHDHIVSTIYSTFGAFYIPLVLILILYYKIYRAARTLYHKRQASRMIKEELNGQVFLESGEKSIKLVSTSYMLEKSLSDPSTDFDRIHSTVKSPRSELKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCEKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRY
UniProt	Q02284
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	5
DrugBank	N/A

Ligand

Name	[125I]lysergide
Molecular formula	C20H24IN3O
IUPAC name	(6aR,9R)-N,N-diethyl-5-(125I)iodanyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
Molecular weight	447.337
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.6
Synonyms	(4R,7R)-N,N-diethyl-10-(125I)iodo-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene-4-carboxamide [125I]N,N-Diethyllysergamide GTPL261 [125I]lysergic acid diethylamide [125I]LSD D0BW9V [125I]lysergamid [ Show all ]
Inchi Key	OBCUQRYIGTWROI-YUPRZBKSSA-N
Inchi ID	InChI=1S/C20H24IN3O/c1-4-24(5-2)20(25)12-9-14-13-7-6-8-16-18(13)15(19(21)22-16)10-17(14)23(3)11-12/h6-9,12,17,22H,4-5,10-11H2,1-3H3/t12-,17-/m1/s1/i21-2
PubChem CID	73754990
ChEMBL	N/A
IUPHAR	261
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Kd	0.98 nM	PMID1328180	IUPHAR

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