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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Probable G-protein coupled receptor 32
Species	Homo sapiens (Human)
Gene	GPR32
Synonym	GPR32 resolvin D1 receptor RvD1 RVDR1
Disease	N/A
Length	356
Amino acid sequence	MNGVSEGTRGCSDRQPGVLTRDRSCSRKMNSSGCLSEEVGSLRPLTVVILSASIVVGVLGNGLVLWMTVFRMARTVSTVCFFHLALADFMLSLSLPIAMYYIVSRQWLLGEWACKLYITFVFLSYFASNCLLVFISVDRCISVLYPVWALNHRTVQRASWLAFGVWLLAAALCSAHLKFRTTRKWNGCTHCYLAFNSDNETAQIWIEGVVEGHIIGTIGHFLLGFLGPLAIIGTCAHLIRAKLLREGWVHANRPKRLLLVLVSAFFIFWSPFNVVLLVHLWRRVMLKEIYHPRMLLILQASFALGCVNSSLNPFLYVFVGRDFQEKFFQSLTSALARAFGEEEFLSSCPRGNAPRE
UniProt	O75388
Protein Data Bank	N/A
GPCR-HGmod model	O75388
3D structure model	This predicted structure model is from GPCR-EXP O75388.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	99
DrugBank	N/A

Ligand

Name	[3H]resolvin D1
Molecular formula	C22H32O5
IUPAC name	(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid
Molecular weight	376.493
Hydrogen bond acceptor	5
Hydrogen bond donor	4
XlogP	3.1
Synonyms	GTPL3934 (4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid RvD1 D05SZG GTPL4356 SCHEMBL13150511 D0P0KG Resolvin D1 [3H]-RvD1 [ Show all ]
Inchi Key	OIWTWACQMDFHJG-LDOXQWQISA-N
Inchi ID	InChI=1S/C22H32O5/c1-2-3-9-14-19(23)15-10-6-4-5-7-11-16-20(24)21(25)17-12-8-13-18-22(26)27/h3-12,15-16,19-21,23-25H,2,13-14,17-18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,12-8-,15-10+,16-11+/t19-,20-,21-/m0/s1
PubChem CID	73755062
ChEMBL	N/A
IUPHAR	3934, 4356
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	0.0088 nM	PMID20080636	IUPHAR
Kd	0.2 nM	PMID20080636	IUPHAR

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