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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Succinate receptor 1
Species	Homo sapiens (Human)
Gene	SUCNR1
Synonym	succinate receptor 1 succinate receptor P2Y purinoceptor 1-like P2Y purinoceptor 1 GPR91 G-protein coupled receptor 91 G protein-coupled receptor 91 SUCNR1 [ Show all ]
Disease	N/A
Length	334
Amino acid sequence	MLGIMAWNATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAFLCTLPMLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFAILISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMCFFYYKIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIASRLGSWKQYQCTQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRDMLMNQLRHNFKSLTSFSRWAHELLLSFREK
UniProt	Q9BXA5
Protein Data Bank	N/A
GPCR-HGmod model	Q9BXA5
3D structure model	This predicted structure model is from GPCR-EXP Q9BXA5.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2150838
IUPHAR	166
DrugBank	BE0002258

Ligand

Name	(S)-2-chlorosuccinic acid
Molecular formula	C4H5ClO4
IUPAC name	(2S)-2-chlorobutanedioic acid
Molecular weight	152.53
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	-0.1
Synonyms	EINECS 224-092-9 SCHEMBL2782669 (2S)-2-chlorobutanedioic acid C-03116 GTPL9634 VC30308 198C338 D23232NSUY L-Chlorosuccinic acid ACM4198338 FCH838986 UNII-D23232NSUY CC-01350 I04-0901 ZINC2018557 4198-33-8 DB-050829 PubChem6255 AKOS017344893 FT-0605208 UNII-E7056CM1PK component QEGKXSHUKXMDRW-REOHCLBHSA-N (S)-Chlorosuccinic acid Chlorosuccinic acid, (S)- KB-04969 [ Show all ]
Inchi Key	QEGKXSHUKXMDRW-REOHCLBHSA-N
Inchi ID	InChI=1S/C4H5ClO4/c5-2(4(8)9)1-3(6)7/h2H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1
PubChem CID	9793861
ChEMBL	N/A
IUPHAR	9634
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	72000.0 nM	PMID28160606	IUPHAR

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