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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Lysophosphatidic acid receptor 3
Species	Mus musculus (Mouse)
Gene	Lpar3
Synonym	Edg7 endothelial differentiation gene 7, lysophosphatidic acid G-protein-coupled receptor 7 LPA receptor 3 LPA-3 LPA3 receptor Lysophosphatidic acid receptor Edg-7 [ Show all ]
Disease	N/A for non-human GPCRs
Length	354
Amino acid sequence	MNECHYDKRMDFFYNRSNTDTADEWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDTSLTASLANLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLAFFIMVAVYVRIYMYVKRKTNVLSPHTSGSISRRRAPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCKQCNVQHVKRWFLLLALLNSVMNPIIYSYKDEDMYNTMRKMICCALQDSNTERRPSRNPSTIHSRSETGSQYLEDSISQGPVCNKNGS
UniProt	Q9EQ31
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	274
DrugBank	N/A

Ligand

Name	D0SH0M
Molecular formula	C16H11NO5
IUPAC name	5-(4-methylphenoxy)-1,3-dioxoisoindole-2-carboxylic acid
Molecular weight	297.266
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.2
Synonyms	5-(4-methylphenoxy)-1,3-dioxoisoindole-2-carboxylic acid GTPL6989 compound 12 [PMID: 19800804]
Inchi Key	QSPCKQSNISDWOH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H11NO5/c1-9-2-4-10(5-3-9)22-11-6-7-12-13(8-11)15(19)17(14(12)18)16(20)21/h2-8H,1H3,(H,20,21)
PubChem CID	73755253
ChEMBL	N/A
IUPHAR	6989
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	2992.0 nM	PMID19800804	IUPHAR

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