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Name | G-protein coupled receptor 55 |
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Species | Homo sapiens (Human) |
Gene | GPR55 |
Synonym | GPR55 |
Disease | N/A |
Length | 319 |
Amino acid sequence | MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG |
UniProt | Q9Y2T6 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9Y2T6 |
3D structure model | This predicted structure model is from GPCR-EXP Q9Y2T6. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1075322 |
IUPHAR | 109 |
DrugBank | BE0005802 |
Name | MLS-0437448.0001 |
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Molecular formula | C11H11N5S |
IUPAC name | [(E)-(5-phenyl-1H-pyrazol-4-yl)methylideneamino]thiourea |
Molecular weight | 245.304 |
Hydrogen bond acceptor | 3 |
Hydrogen bond donor | 3 |
XlogP | 1.2 |
Synonyms | AC1NSL0H HMS1583O17 [[(Z)-(3-phenylpyrazol-4-ylidene)methyl]amino]thiourea AKOS005444153 ST50912622 [ Show all ] |
Inchi Key | CNUFVDRGRFSWEU-VGOFMYFVSA-N |
Inchi ID | InChI=1S/C11H11N5S/c12-11(17)16-14-7-9-6-13-15-10(9)8-4-2-1-3-5-8/h1-7H,(H,13,15)(H3,12,16,17)/b14-7+ |
PubChem CID | 135446678 |
ChEMBL | CHEMBL1701030 |
IUPHAR | N/A |
BindingDB | 75871 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | <32000.0 nM | , PubChem BioAssay data set | BindingDB,ChEMBL |
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